Source+3

[](about resistance and how it occurs)
 * "General Background: About Antibiotic Resistance." //Tufts University//. Web. 05 Apr. 2011.
 * "Antibiotic resistance occurs when an antibiotic has lost its ability to effectively control or kill bacterial growth; in other words, the bacteria are "resistant" and continue to multiply in the presence of therapeutic levels of an antibiotic." (paragraph 1)
 * "Some bacteria are naturally resistant to certain types of antibiotics." (paragraph 4)
 * "However, bacteria may also become resistant in two ways: 1) by a genetic mutation or 2) by acquiring resistance from another bacterium." (paragraph 4)
 * "Different genetic mutations yield different types of resistance." (paragraph 5)
 * "Some mutations enable the bacteria to produce potent chemicals (enzymes) that inactivate antibiotics, while other mutations eliminate the cell target that the antibiotic attacks." (paragraph 5)
 * "Still others close up the entry ports that allow antibiotics into the cell, and others manufacture pumping mechanisms that export the antibiotic back outside so it never reaches its target" (paragraph 5)
 * "Genetically, antibiotic resistance spreads through bacteria populations both "vertically," when new generations inherit antibiotic resistance genes, and "horizontally," when bacteria share or exchange sections of genetic material with other bacteria." (paragraph 8)
 * "Yes, antibiotic resistance traits can be lost, but this reverse process occurs more slowly. If the [|selective pressure] that is applied by the presence of an antibiotic is removed, the bacterial population can potentially revert to a population of bacteria that responds to antibiotics." (paragraph 9)
 * "By undergoing a simple mating process called "conjugation," bacteria can transfer genetic material, including genes encoding resistance to antibiotics (found on [|plasmids] and [|transposons]) from one bacterium to another." (paragraph 6)
 * "The resistance traits from one bacterium are packaged into the head portion of the virus. The virus then injects the resistance traits into any new bacteria it attacks." (paragraph 6)
 * "Bacteria also have the ability to acquire naked, "free" DNA from their environment." (paragraph 6)
 * "Because bacteria can collect multiple resistance traits over time, they can become resistant to many different families of antibiotics." (paragraph 7)
 * "When an antibiotic is used, bacteria that can resist that antibiotic have a greater chance of survival than those that are "susceptible."" (paragraph 2)
 * "Susceptible bacteria are killed or inhibited by an antibiotic, resulting in a [|selective pressure] for the survival of resistant strains of bacteria." (paragraph 2)
 * "Some resistance occurs without human action, as bacteria can produce and use antibiotics against other bacteria, leading to a low-level of natural selection for resistance to antibiotics." (paragraph 3)